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Consumer Information - Index Retroperitoneal fibrosis (RPF) is characterized by the development of extensive fibrosis throughout the retroperitoneum, typiy centered over the anterior surface of the fourth and fifth lumbar vertebrae and resulting in entrapment and obstruction of retroperitoneal structures, notably the ureters. RPF can also be associated with Crohn disease, ulcerative colitis, and sclerosing cholangitis. The diagnosis of RPF requires a hh degree of suspicion, and the evaluation of patients with presumed idiopathic RPF includes ruling out secondary RPF due to malnancy, infection, retroperitoneal injury, or drugs. You have fibroid tumors of the uterus. • you have gallbladder or pancreatic disease. prednisone. • sedatives and hypnotics e.g. barbiturates.
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